| Primary Identifier | MGI:3836289 | Allele Type | QTL |
| Gene | Bxs6 | Strain of Origin | BXSB/MpJ |
| Is Recombinase | false | Is Wild Type | false |
| description | Bxs6 interacts with Gpab1 on chromosome 9. Homozygosity for BXSB/MpJ alleles at Bxs6 in conjunction with C57BL/6 alleles at Gpab1 further enhances gp70 autoantibody titers and gp70 immune complex levels. The Yaa locus on chromosome Y enhances nephritis phenotypes in the presence of Bxs6. |
| molecularNote | This allele confers increased gp70 autoantibody titers, increased levels of gp70 immune complex and increased incidence and severity of glomerulonephritis compared to C57BL/10Ola. |
