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Allele : Tg(IGH-Btk)1Witt transgene insertion 1, Owen N Witte

Primary Identifier	MGI:3836559	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(IGH-Btk)1Witt
Strain of Origin	C57BL/6 x C3H	Is Recombinase	false
Is Wild Type	false

molecularNote

This transgene consists of the murine H chain Ig enhancer and the human H chain Ig promoter driving expression of a murine Btk cDNA.

mutations:
Insertion

earliestPublication:
Satterthwaite AB, et al. (1997) Btk dosage determines sensitivity to B cell antigen receptor cross-linking. Proc Natl Acad Sci U S A 94(24):13152-7

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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