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Allele : Cdc25a<tm1.1Hpw> cell division cycle 25A; targeted mutation 1, Helen Piwnica-Worms
Primary Identifier  MGI:3836586 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdc25a
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was introduce 5' of exon 1 and a loxP-flanked selection cassette was introduced to intron 3 via 129X1/SvJ-derived RW4 embryonic stem (ES) cells. ES cell clones containing the recombinant allele were expanded and transiently transfected with a plasmid encoding Cre recombinase under the control of the CMV promoter to remove exons 1-3 and the selection cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Cdc25A<->,
  • A<->,
  • A<->,
  • Cdc25A<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories





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