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Allele : Tg(ACTB-Twnk*)DSuom transgene insertion D, Anu Suomalainen

Primary Identifier  MGI:3836897 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ACTB-Twnk*)DSuom
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The human promoter was used to drive ubiquitous expression of the mouse gene with a silent point mutation at position 1077 (c.1077C->G) that forms a restriction enzyme site and allows for the insertion of 39 nucleotides. This produces a duplication of amino acids 353 to 365. Four lines were produced (C, D, E, and F) with line D selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • Twinkle<dup>,
  • Tg(ACTB-Peo1*)DSuom,
  • Tg(ACTB-Peo1*)DSuom,
  • Twinkle<dup>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories