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Allele : Tg(Myh7-RARA/lacZ)30Mcco transgene insertion 30, Melissa C Colbert

Primary Identifier  MGI:3838149 Allele Type  Transgenic
Attribute String  Constitutively active, Humanized sequence, Inserted expressed sequence, Reporter Gene  Tg(Myh7-RARA/lacZ)30Mcco
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse promoter was used to drive cardiac-specific expression of a human cDNA truncated at amino acid 448 and fused in frame via a collagen linker to lacZ. This truncation and fusion produces a constitutively active form. Two lines (30 and 32) were created. Line 30 has 12 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • beta-MyHC-hRARalpha-CB,
  • beta-MyHC-hRARalpha-CB
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories