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Allele : Thrb<tm1Mkni> thyroid hormone receptor beta; targeted mutation 1, Marlies Knipper

Primary Identifier  MGI:3836780 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Thrb
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were introduced 5' and 3' of exon 8 and an FRT site flanked neomycin resistance gene cassette was introduced downstream of the 3' loxP site in intron 8. The neo cassette was then removed by Flp-mediated recombination leaving behind a single FRT site.
  • mutations:
  • Insertion
  • synonyms:
  • Thrb<tm1.1Sasr>,
  • TRbeta<flox>,
  • TRbeta<lox>,
  • TRbeta<flox>,
  • TRbeta L2,
  • TRbeta L2,
  • Thrb<tm1.1Sasr>,
  • TRbeta<lox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories