| Primary Identifier | MGI:3837451 | Allele Type | Transgenic |
| Attribute String | Inducible, Recombinase | Gene | Tg(Tek-icre/ERT2)1Soff |
| Strain of Origin | FVB/N | Induced With | tamoxifen |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A tamoxifen-inducible icre recombinase gene and FRT-flanked beta-lactamase gene were inserted into the ATG start site of the murine Tek gene located on a BAC. After Flpe-mediated excision of the beta-lactamase gene, the targeted BAC was injected into FVB/N oocytes. Cre expression was detected in endothelial cells of numerous organs after treatment with tamoxifen. |
