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Allele : Ccm2<tm1Etl> cerebral cavernous malformation 2; targeted mutation 1, Elisabeth Tournier-Lasserve
Primary Identifier  MGI:3837678 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ccm2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed GFP/hygromycin resistance cassette was placed upstream of exon 3 and an additional loxP site was placed downstream of exon 4. Chimeric mice were bred with Tg(rtetR-TetO-cre)40Mhz mice to remove the selection cassette and leave exons 3 and 4 flanked by loxP sites. Protein expression was unaffected in homozygotes.
  • mutations:
  • Insertion
  • synonyms:
  • Ccm2<flox>,
  • Ccm2<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories





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