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Allele : Ccm2<tm1.1Etl> cerebral cavernous malformation 2; targeted mutation 1.1, Elisabeth Tournier-Lasserve

Primary Identifier  MGI:3837686 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ccm2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed GFP/hygromycin resistance cassette was placed upstream of exon 3 and an additional loxP site was placed downstream of exon 4. Chimeric mice were bred with Tg(rtetR-TetO-cre)40Mhz mice to remove the selection cassette and exons 3 and 4. Gene inactivation was confirmed by a lack of protein detected in immunoblot analysis of E9.5 embryo lysates.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ccm2<->,
  • Ccm2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories