| Primary Identifier | MGI:3840910 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Foxo1 |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted into the XbaI restriction site upstream of exon 1 and a frt-flanked neoymycin cassette with a 3' loxP site was inserted downstream of exon 1. Mice were crossed with transgenic Flipase to remove the neomycin cassette, leaving exon 1 floxed. Protein expression was unaffected as determined by immunoblot analysis of homozygote lymphocyte extracts. |
