| Primary Identifier | MGI:3839938 | Allele Type | Targeted |
| Gene | Mre11a | Transmission | Germline |
| Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 5 was replaced with one in which a C to A substitution results in the amino acid substitution of histidine with asparagine at position 129 (p.H129N) in the encoded protein. This mutation occurs in nuclease motif III. A loxP site flanked neomycin resistance gene cassette was inserted into intron 5 and subsequently removed by transient cre expression in ES cells. |
