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Allele : Mre11a<tm2.2Dof> MRE11A homolog A, double strand break repair nuclease; targeted mutation 2.2, David O Ferguson

Primary Identifier  MGI:3839940 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mre11a
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Germ line, cre mediated recombination was used to remove the neo cassette and exon 5. This deletion causes a frame shift and generates multiple stop codons after eight amino acids. The absence of protein expression was confirmed in mouse embryonic fibroblast extracts.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Mre11<delta>,
  • Mre11<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories