Primary Identifier | MGI:3839940 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Mre11a |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Germ line, cre mediated recombination was used to remove the neo cassette and exon 5. This deletion causes a frame shift and generates multiple stop codons after eight amino acids. The absence of protein expression was confirmed in mouse embryonic fibroblast extracts. |