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Allele : Gt(ROSA)26Sor<tm1(CAG-lacZ,-EGFP)Glh> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, David J Goldhamer

Primary Identifier  MGI:3840211 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6J)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A vector containing a CAG promoter driving expression of a floxed neo/STOP cassette, frt flanked lacZ gene with 3 polyadenylation sequences (secondary STOP cassette), and an EGFP gene was inserted into the locus. Expression of lacZ requires cre mediated removal of the primary STOP cassette whereas expression of EGFP requires cre mediated removal of the primary stop cassette and flp mediated removal of the secondary STOP cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Rosa26-CAG-loxP-STOP-loxP,
  • R-GFP,
  • R26<NZG>,
  • R-GFP,
  • Rosa26-CAG-loxP-STOP-loxP,
  • R26<NZG>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

45 Publication categories