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Allele : Gt(ROSA)26Sor<tm3(SNCA*E46K)Djmo> gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Darren Moore
Primary Identifier  MGI:3840600 Allele Type  Targeted
Attribute String  Conditional ready, Humanized sequence, Inserted expressed sequence, No functional change Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
description  The original reference states that 129/SvJ-derived embryonic stem cells were used.
molecularNote  A targeting vector was designed with an SV40 splice acceptor, a loxP-flanked STOP cassette (PGK-neo and triple SV40 transcriptional termination sequence), a human alpha-synuclein cDNA bearing a familial Parkinson's disease-linked E46K missense mutation (SYNE46K), and a bovine polyadenylation signal.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26-SynE46K<Tg>,
  • ROSA26-Syn-E46K,
  • ROSA26-Syn-E46K,
  • ROSA26-SynE46K<Tg>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories





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