Primary Identifier | MGI:3840270 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Ccn2 |
Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NTac)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of exons 3, 4 and a part of exon 5 coding for von Willebrand factor type C domain with a transmembrane domain-lacZ/neo cassette via homologous recombination. The neo selection minigene was flanked with LoxP sites. Resulting allele produces a Ctgf N terminus/beta-gal fusion protein. |