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Allele : Mecp2<tm3.1Jae> methyl CpG binding protein 2; targeted mutation 3.1, Rudolf Jaenisch
Primary Identifier  MGI:3840525 Allele Type  Targeted
Gene  Mecp2 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Exons 3 and 4 were replaced by a floxed neo/STOP cassette and exons containing nucleotide substitutions that result in the amino acid substitutions of alanine for serine at positions 421 and 424 (S421A;S424A). Cre-mediated recombination was used to remove the neo/STOP cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Mecp2<S421A;S424A>,
  • Mecp2<S421A;S424A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories





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