Primary Identifier | MGI:3840818 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Del(2Hoxd12-Hoxd13)41Ddu |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Germ line, cre mediated recombination between Hoxd12tm2Ddu and Hoxd13tm2Ddu maintained in cis results in the deletion of the 3' end of exon 1 Hoxd12tm2Ddu through the lacZ insertion in exon 1 Hoxd12tm2Ddu. The lacZ cassette inserted into Hoxd13 is retained. In situ hybrizidation confirmed expression of the fusion transcript in a similar pattern observed for Hoxd11. |