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Allele : Hoxd<tm17Ddu> homeobox D cluster; targeted mutation 17, Denis Duboule
Primary Identifier  MGI:3840830 Allele Type  Targeted
Attribute String  Null/knockout Gene  Hoxd
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  The 5 Kb intergenic region between Hoxd13 and Hoxd12 was replaced with the corresponding 3 Kb sequence from zebrafish. A 5' floxed neo cassette was removed in vitro. Whole mount in situ hybridization confirmed reduced expression of Hoxd12 but normal expression of Hoxd11 and Hoxd13.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • HoxD<(12-13)Fi>,
  • HoxD<(12-13)Fi>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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