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Allele : Tg(Prrx1-Sox9,-lacZ)1Haak transgene insertion 1, Haruhiko Akiyama

Primary Identifier	MGI:3840957	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Prrx1-Sox9,-lacZ)1Haak
Strain of Origin	C57BL/6 x DBA/2	Is Recombinase	false
Is Wild Type	false

molecularNote

This transgene consists of a 2.4 kg fragment of the Prrx1 limb specific promoter driving expression of a 3x hemagglutinin tagged Sox9 cDNA followed by an IRES lacZ cassette. LacZ expression is seen in the limb buds starting at E9.5.

mutations:
Insertion

synonyms:
Prx1-Sox9/LacZ,
Prx1-Sox9/LacZ

earliestPublication:
Akiyama H, et al. (2007) Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol 26(4):224-33

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

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