| Primary Identifier | MGI:3841702 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(CAG-ANGPT1*)5Yo |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A transgene construct was produced in which a modified human Angiopoietin 1 cDNA (COMP-Ang1) was separated from the CAG promoter by a loxP-blasticidineS cDNA-polyA-loxP sequence. The construct was injected into TT2 ES cells. A cre-expressing plasmid was introduced into the transfected ES cells and 2 clones demonstrated high levels of COMP-Ang1 expression. Transgenic mice were generated from clone 5. When crossed to a suitable cre-expressing line, the offspring will express the modified form of human angiopoietin 1. |
