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Allele : Tg(Myh6-PRKAG2*N488I)4623Jse transgene insertion 4623, Jonathan G Seidman

Primary Identifier  MGI:3841167 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Myh6-PRKAG2*N488I)4623Jse
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse promoter was used to drive cardiac-specific expression of the human gene with an T to A substitution at position 1553 that results in the amino acid substitution of asparagine with isoleucine at position 488 (N488I). Eight lines were created with line 4623 selected as the representative line. This line carried 20 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • TG<N488I>,
  • TG<N488I>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories