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Allele : Tg(Myh6/tetO-PRKAG2*N488I)1Chib transgene insertion 1, Charles I Berul

Primary Identifier  MGI:3841177 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Inserted expressed sequence Gene  Tg(Myh6/tetO-PRKAG2*N488I)1Chib
Strain of Origin  Not Specified Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  A fusion promoter with tetO was used to drive repressible, cardiac expression of the human gene with an T to A substitution at position 1553 that results in the amino acid substitution of asparagine with isoleucine at position 488 (N488I). Thirteen lines were created with 2 exhibiting robust expression and phenotype. No line numbers were given.
  • mutations:
  • Insertion
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories