Primary Identifier | MGI:3842979 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Ihh |
Transmission | Germline | Strain of Origin | 129S/SvEv |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line = L4. |
molecularNote | A 397G>A substitution was introduced into exon 1 and a floxed neo cassette was inserted into intron 1 via homologous recombination. Cre mediated recombination then removed the neo cassette leaving a single loxP site in intron 1. The point mutation results in a E95K mutation in the protein. |