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Allele : Avp<tm1Lja> arginine vasopressin; targeted mutation 1, J Larry Jameson
Primary Identifier  MGI:3843457 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Avp
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted in intron 1 and a C67X nonsense mutation was inserted in exon 2 via homologous recombination. The floxed neo cassette was then removed by Cre mediated recombination. RT-PCR confirmed the expression of mutant transcript in the hypothalamus.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Avp<C67X>,
  • Avp<C67X>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories





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