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Allele : Tg(Aqp2-icre)1Gsc transgene insertion 1, Gunther Schutz
Primary Identifier  MGI:3843825 Allele Type  Transgenic
Attribute String  Recombinase Gene  Tg(Aqp2-icre)1Gsc
Strain of Origin  FVB/N Is Recombinase  true
Is Wild Type  false
molecularNote  A PAC (RPCI21) containing a 125 kb 5'upstream region and 31.2 kb 3'downstream region of the mouse Aqp2 gene was modified by ET-recombination so that a cassette encoding a codon-improved cre recombinase sequence was inserted at the ATG of Aqp2. This modified fragment was injected into FVB/N oocyte pronuclei. A founder line with 2 copies of the transgene was established.
  • mutations:
  • Insertion
  • synonyms:
  • AQP2Cre,
  • AQP2Cre,
  • Aqp2::iCre,
  • Aqp2::iCre
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

14 Publication categories





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