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Allele : Tg(Thy1-Nlgn1)6Hnes transgene insertion 6, Rochelle Hines
Primary Identifier  MGI:3844457 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Thy1-Nlgn1)6Hnes
Strain of Origin  (C57BL/6 x CBA)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The TgNL1 transgene was designed with a modified regulatory region of the "murine thy1.2 gene" (extending from the promoter to the intron following exon 4, excluding exon 3 and its flanking introns) upstream of a hemagglutinin-tagged mouse neuroligin 1 (Nlgn1 or NL1) cDNA. This transgene was injected into (C57BL/6xCBA)F1 cells. Transgenic founders were bred with C57BL/6 and mice from founder line 6 (TgNL1.6) were found to have approximately two-fold increase in NL1 expression.
  • mutations:
  • Insertion
  • synonyms:
  • TgNL1.6,
  • TgNL1,
  • TgNL1,
  • TgNL1.6
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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