Primary Identifier | MGI:3843489 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Thy1-UBB*)8630Fwvl |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A transgenic construct containing cDNA encoding the mutant human ubiquitin B, UBB+1 sequence (in the +1 reading frame), under the direction of the mouse Thy1.2 promoter was injected into fertilized FVB/N mouse eggs. Founder line 8630 with 2 copies of the transgene was subsequently established. mRNA levels for UBB+1 are 67% of endogenous Ubb mRNA levels. |