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Allele : Tg(ACTB-TNFRSF6B)754Jwu transgene insertion 754 Jiangping Wu

Primary Identifier  MGI:3843671 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(ACTB-TNFRSF6B)754Jwu
Strain of Origin  C3H x C57BL/6 Is Recombinase  false
Is Wild Type  false
description  Line 17139 exhibits a phenotype similar to Line 754, including lymphadenopathy, pathologies in skin, kidney and liver and a shortened lifespan in females.
molecularNote  The construct consists of human full length Dcr3 (TNFRSF6B) cDNA flanked by human beta actin promoter and beta actin poly(A) signal. The construct was injected into fertilized eggs from C3H x C57BL/6 mice. Line 754 was established and analyzed further.
  • mutations:
  • Insertion
  • synonyms:
  • DcR3 Tg,
  • DcR3 Tg
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

1 Driven By

5 Publication categories