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Allele : Ptgs2<tm1Gaf> prostaglandin-endoperoxide synthase 2; targeted mutation 1, Garret A FitzGerald
Primary Identifier  MGI:3844713 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Ptgs2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 6, 7, and 8 that are critical for enzymatic function were flanked by loxP sites. PGE-2 production by activated peritoneal macrophages is unaffected in mice homozygous for this allele, indicating that gene function was not disrupted.
  • mutations:
  • Insertion
  • synonyms:
  • CM-COX-2,
  • COX-2<flox>,
  • CM-COX-2,
  • COX-2<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

21 Publication categories





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