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Allele : Tg(CD2-Stat6*V625A*T626A)78Mhk transgene insertion 78, Mark H Kaplan

Primary Identifier  MGI:3845883 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(CD2-Stat6*V625A*T626A)78Mhk
Strain of Origin  C3H Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Ocular Atopic Dermatitis J:230018.
molecularNote  This transgene expresses the human STAT6 gene, with codons V625 and T626 mutated to express alanine and a C-terminal FLAG tag added, under transcriptional control of the CD2 locus control region. This promoter restricted expression of the transgene primarily to B and T lymphocytes. In addition to line 78, founder line 24 was also established.
  • mutations:
  • Insertion
  • synonyms:
  • Stat6VT,
  • StatVT,
  • Stat6VT,
  • StatVT
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

17 Publication categories