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Allele : Pld2<tm1(KOMP)Vlcg> phospholipase D2; targeted mutation 1, Velocigene

Primary Identifier  MGI:3847515 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Pld2
Transmission  Germline Strain of Origin  C57BL/6NTac
Is Recombinase  false Is Wild Type  false
Project Collection  KOMP-Regeneron
description  J: 216114 and, presumably, J:215283 describe mice created using the 11541B-D1 mutant ES cell line.
molecularNote  The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 16757bp between positions 70431675-70448431 of Chromosome 11 (Build GRCm39). RT-PCR analysis revealed absence of mRNA transcripts in homozygous mutant platelets. Western blot analysis confirmed the absence of protein in mutant spleen and brain tissues.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Pld2<->,
  • Pld2<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories