| Primary Identifier | MGI:3849605 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Kera-cre)KC4.3Wwk |
| Strain of Origin | FVB/N | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | A minigene containing a 3.2 kb fragment 5' of the transcription start site of the Kera gene, exon 1 (172 bp), intron 1 (1.4 kb), exon 2 (7 bp) preceding the ATG start codon of the Kera mRNA, and a cre minigene with IRES and nuclear localization sequences (NLS) followed by the SV40 polyadenylation (pA) signal, was injected into FVB/N oocytes. Mice were crossed with R26R reporter mice to assess cre activity. Founder line KC4.3, showing strong expression and line KC4.1 with moderate expression were characterized further. |
