Primary Identifier | MGI:3849832 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Lck-Tnfsf14)24Yxf |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Tnfsf14 coding sequence was driven by the proximal Lck promoter and human CD2 enhancer with human growth hormone gene (polyadenylation site) included downstream. Lines 24 and 27 in a C57BL/6 background were selected for further investigation with similar phenotypes observed in both lines. Expression in lymphocytes was confirmed by flow cytometry analysis of lymphocytes. |