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Allele : Pidd1<tm1.1Anvi> p53 induced death domain protein 1; targeted mutation 1.1, Andreas Villunger

Primary Identifier  MGI:3847893 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pidd1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 3-15 of the gene were replaced by the open reading frame of beta-galactosidase followed by a loxP flanked neo cassette. The loxP flanked neo cassette was removed in vivo by cre-mediated deletion. RT-PCR analysis confirmed the absence of mRNA in thymocytes and MEFs. Absence of protein product was confirmed by western blot of thymocyte extracts derived from homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • pidd<->,
  • pidd<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories