Primary Identifier | MGI:3848915 | Allele Type | Transgenic |
Attribute String | Conditional ready, Inserted expressed sequence | Gene | Tg(CAG-Nog)1Ych |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The coding sequence of Nog was cloned into a vector in front of an IRES-EGFP sequence under control of the chick beta-actin promoter and the CMV immediate-early enhancer. A STOP cassette flanked by loxP sites was inserted between the CAG promoter and the Noggin sequence. Excision of the STOP cassette by cre recombinase permits expression of Noggin. |