Primary Identifier | MGI:3849991 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Erbin |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene trap vector pGT2LxF, which contains a beta-geo cassette, inserted downstream of exon 20. The predicted fusion protein, containing amino acids 1 through 693, lacks the PDZ domain found in the C-terminus of the endogenous protein. The expression of the fusion protein lacking the PDZ domain was confirmed by western blot analysis on brain extracts. |