| Primary Identifier | MGI:3851565 | Allele Type | Transgenic |
| Attribute String | Dominant negative, Inducible, Inserted expressed sequence | Gene | Tg(Myh6/tetO-PRKCA*)1Jmk |
| Strain of Origin | FVB/N | Induced With | doxycycline/tetracycline |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The rabbit PRKCA cDNA carrying the dominant negative L368A mutation was fused to the cardiac-specific alpha myosin heavy chain (Myh6) mouse promoter. The promoter is minimally active/attenuated through the ablation of three GATA sites and two thyroid-like response elements. Seven copies of tetracycline-responsive promoter element (tetO) are fused to the promoter. |
