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Allele : Tg(Myh6-Map2k3*)1Jmol transgene insertion 1, Jeffery D Molkentin

Primary Identifier  MGI:3851571 Allele Type  Transgenic
Attribute String  Dominant negative, Inserted expressed sequence Gene  Tg(Myh6-Map2k3*)1Jmol
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  he mouse cardiac alpha myosin heavy chain (Myh6) promoter drives expression of a dominant negative Ser189Ala/Ser193Ala form of mouse MKK3 (Map2k3). Two lines were generated and one was chosen for further characterization.
  • mutations:
  • Insertion
  • synonyms:
  • dnMKK3,
  • dnMKK3
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories