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Allele : Muc2<M1Btlr> mucin 2; mutation 1, Bruce Beutler

Primary Identifier  MGI:3851216 Allele Type  Chemically induced (ENU)
Gene  Muc2 Inheritance Mode  Semidominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  This mutation was identified in a screen of G3 progeny of an ENU mutagenized male mouse for susceptibility to induction of colitis by dextran sulfate sodium (DSS) (DSS-induced Colitis Screen). The mutation comprises a G to T transversion at nucleotide position 1711, in the 13th of the gene's 47 exons. It is predicted to result in substitution, at amino acid position 561, of phenylalanine for a conserved cysteine in the second von Willebrand factor type D (VWFD) domain of the protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Schlendrian,
  • Schlendrian
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

3 Publication categories