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Allele : Batf<tm1.1Kmm> basic leucine zipper transcription factor, ATF-like; targeted mutation 1.1, Kenneth M Murphy

Primary Identifier	MGI:3851385	Allele Type	Targeted
Attribute String	Null/knockout	Gene	Batf
Transmission	Germline	Strain of Origin	129S6/SvEvTac
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 1 and 2 were replaced with a floxed neomycin cassette. The neomycin cassette was subsequently removed by transient expression of cre recombinase. No protein product was detected by immunoblot analysis of homozygote splenocyte or Th17 cells.

mutations:
Insertion,
Intragenic deletion

cellLines:
Not Specified

earliestPublication:
Schraml BU, et al. (2009) The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature 460(7253):405-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

5 Carried By

0 Driven By

36 Publication categories

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