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Allele : Tg(Mt1-CBS*S466L)EB86Waku transgene insertion EB86, Warren Kruger

Primary Identifier  MGI:3851386 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Mt1-CBS*S466L)EB86Waku
Strain of Origin  (C57BL/6 x C3H)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The mouse promoter was used to drive zinc-inducible expression of the human cDNA with a point mutation that results in the amino acid substitution of lysine for serine at position 466. This mutation was identified in patients with homocystinuria. Three lines were created and line EB86 was selected as the representative line.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-S466L,
  • Tg-S466L
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories