| Primary Identifier | MGI:3851404 | Allele Type | Transgenic |
| Attribute String | Hypomorph, Inserted expressed sequence | Gene | Rfx4 |
| Strain of Origin | C57BL/6NTac | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Two tandem copies of concatenated transgene consisting of human CYP2J2 cDNA with mouse alpha-MHC promoter and human growth hormone intron and polyA sequence was inserted into intron of mouse Rfx4 gene. This transgene is one of six lines described in J:101489. Northern blot analysis revealed that variant form of the transcript RFX4_v3 expression was absent in brain whereas other two forms, variant 1 and 2, expression were not affected. This is an isoform specific null allele. |
