Primary Identifier | MGI:3852356 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Npas3 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Part of exon 4 was replaced with a neo cassette. This deletion is predicted to produce a protein lacking part of the PAS-A domain and all of the PAS-B domain. The absence of transcript expression was confirmed by QRT-PCR on E12.5 lung extracts. |