| Primary Identifier | MGI:3852645 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Sox17 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A targeting vector containing a mini gene locus with a codon improved cre recombinase cDNA with a translational stop codo, splice donor site, artificial intron and an exon encoding the SV40 polyadenylation signal followed by an FRT-flanked PGK-neo cassette in the opposite orientation was introduced into exon 1 of Sox17 by homologous recombination in TBV2 ES cells. Germline chimeras were generated and the neo cassette was excised by crossing these with Flpe mice. |
