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Allele : L2hgdh<Gt(DC0625)Wtsi> L-2-hydroxyglutarate dehydrogenase; gene trap DC0625, Wellcome Trust Sanger Institute

Primary Identifier  MGI:3869865 Allele Type  Gene trapped
Attribute String  Hypomorph Gene  L2hgdh
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Sanger Inst. Gene Trap Res.
molecularNote  Trapped gene association determined by genome coordinate overlap and strand. The gene trap vector inserted in the third intron, resulting in the production of a fusion transcript encoding the first 137 amino acid residues of L2hgdh followed by beta-geo. qPCR indicates low but detectable levels of transcripts indicating that the polyadenylation signal in the inactivation cassette is leaky. In addition, a small amount of readthrough transcript is synthesized and spliced as wild-type RNA.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories