| Primary Identifier | MGI:3869865 | Allele Type | Gene trapped |
| Attribute String | Hypomorph | Gene | L2hgdh |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Sanger Inst. Gene Trap Res. |
| molecularNote | Trapped gene association determined by genome coordinate overlap and strand. The gene trap vector inserted in the third intron, resulting in the production of a fusion transcript encoding the first 137 amino acid residues of L2hgdh followed by beta-geo. qPCR indicates low but detectable levels of transcripts indicating that the polyadenylation signal in the inactivation cassette is leaky. In addition, a small amount of readthrough transcript is synthesized and spliced as wild-type RNA. |