Primary Identifier | MGI:4038368 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Chchd4 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Trapped gene association determined by genome coordinate overlap and strand. Immunoblot analysis confirmed the absence of protein expression in extracts from homozygous mutant embryos staged at E5.5-E6.0. Adult heterozygotes showed a ~50% reduction of CHCHD4 protein levels in various organs with no detectable changes in the abundance of AIFM1 protein. |