| Primary Identifier | MGI:7311638 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(COL2A1*R519C)#Afe |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene consists of a fragment of human genomic DNA encoding COL2A1 with an arginine 519 cysteine (C to T) mutation from skin fibroblasts from a patient with osteoarthritis with mild chondrodysplasia. The fragment includes 4.5 kb of 5' upstream regulatory sequence and 3.0 kb of 3' downstream sequences past the major polyadenylation signal. No line numbers identified but the founder selected carried 2 copies of the transgene. |
