| Primary Identifier | MGI:2180373 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Atf4 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = HM1 (129P2/OlaHsd-Hprtb-m3) or R1 ((129X1/SvJ x 129S1/Sv)F1-Kitl+). The data presented in J:74479 were obtained using R1 ES cells, though the authors report that they also generated mice with targeted alleles using HM1 ES cells. |
| molecularNote | Exons 2 and 3, comprising the entire coding region, were replaced with a targeting construct containing a neomycin resistance gene. Expression analysis confirmed the absence of transcript in homozygous mutant mice. |
