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Allele : Hsd17b11<Gt(OST237628)Lex> hydroxysteroid (17-beta) dehydrogenase 11; gene trap OST237628, Lexicon Genetics

Primary Identifier  MGI:4245470 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Hsd17b11
Transmission  Germline Strain of Origin  129S5/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
description  See also, data as provided by Lexicon Genetics, Inc.
molecularNote  Trapped gene association determined by genome coordinate overlap and strand. The Hsd17b11 gene consists of 7 exons. Retroviral insertion disrupted the gene prior to the exon encoding amino acid 55 in a protein of 298 amino acids (NCBI accession number NP_444492). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice.
  • mutations:
  • Insertion of gene trap vector
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories