Primary Identifier | MGI:4245470 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Hsd17b11 |
Transmission | Germline | Strain of Origin | 129S5/SvEvBrd |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Lexicon |
description | See also, data as provided by Lexicon Genetics, Inc. |
molecularNote | Trapped gene association determined by genome coordinate overlap and strand. The Hsd17b11 gene consists of 7 exons. Retroviral insertion disrupted the gene prior to the exon encoding amino acid 55 in a protein of 298 amino acids (NCBI accession number NP_444492). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. |